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Furthermore, the inclusion of a drug can potentially lead to a reduction in the dosage of other medication, thereby improving safety

In this case, the inhibition of that switch at the IgG4 level disturbs the ratio of IgG4 to IgE in favor of the former

The respiratory region, which forms the largest part of the nasal cavity, is highly vascularised, allowing drugs deposited there to be rapidly absorbed into the systemic circulation and potentially reach the brain after crossing the BBB (Jeong et al., 2023)

Furthermore, we equipped our organ perfusion system with an adsorbing hemofilter able to remove cytokines and to avoid fat embolism