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[DOI] [PMC free article] [PubMed] [Google Scholar] 416.Pfaff E., Kessler T., Balasubramanian G.P., Berberich A., Schrimpf D., Wick A., Debus J., Unterberg A., Bendszus M., Herold-Mende C., et al

By downregulating PPAR, miR-21 in hepatocytes together with miR-34a could promote TG accumulation in the early stages of MASLD but also induce inflammation and fibrosis progression [290, 307]

doi: 10.1038/s41443-020-00374-8 43 LinHCYangWLZhangJLDaiYTWangR

Additionally, cases of ME/CFS have also been recorded post-immunization (163) and many patients are fearful that vaccinations will worsen their already dysfunctional immune system and cause symptom exacerbation (164)