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Trended back up over the summer months a bit

202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione
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doi: 10.1007/s10620-022-07487-8 Small intestinal bacterial overgrowth: Clinical manifestations and diagnosis UpToDate [Internet]

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