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Figure 4 Table 3 List of mechanisms of resistance to anti-angiogenic therapies and ways to target them along with the outcomes associated with each approach
Ann Intern Med 2004;140(7):501509

Crizotinib versus chemotherapy in advanced ALK-positive lung cancer

The authors discuss how the synergistic mechanisms of the two drugs lead to superior weight loss and cardiometabolic improvements, positioning the combination as a significant advance in the treatment of obesity and type 2 diabetes
