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[DOI] [PubMed] [Google Scholar] 71.ALS CNTF Treatment Study Group

When the manufacturer Johnson & Johnson discontinued the product in 2014, it caused a backlash of anger from long-term customers, and the toothpaste began to sell for many times the original price on the auction website eBay

These immune responses are depending on several factors (e.g., species, dose route, dose level) and have relevance to hypersensitivity, vasculitis, and unwanted antibody production

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The PIs provide supporting data and specific information related to the updates (In each PI, see especially Section 5, Warnings and Precautions, and Section 8.1, Use in Specific Populations Pregnancy)