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Remarkably, a single mutation in the ND4 subunit of complex I is adequate to trigger LHON, as elucidated in a study on mice
doi: 10.1016/j.tins.2018.04.005 8

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Hildrum B., Mykletun A., Hole T., Midthjell K., Dahl A.A
The effects of a platelet-rich plasma (PRP) injection generally last between six and nine months, though individual results may vary

Park KH, Kim SW, Kim KD, Paick JS
