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Shaking the vial can damage the fragile peptide chains, a process called denaturation

Park S, Lim W, Bazer FW, Song G (2018) Naringenin suppresses growth of human placental choriocarcinoma via reactive oxygen species-mediated P38 and JNK MAPK pathways

Lancet 380 , 660667 (2012)

In orthopedics, postmenopausal osteoporosis (PMOP) is associated with a significant decline in the diversity and abundance of intestinal microbial communities in a clinical study enrolling 106 individuals, while bone loss was positively correlated with the decrease in genera Allisonella , Klebsiella , and Megasphaera (13)

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