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However clinical evidence is limited and not definitive
However, the volatility of 2,5-DHAP under high vacuum restricts its prolonged use
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Microneedling The microneedling technique uses very thin needles to create microinjuries on the skin, inducing reparative/regenerative processes similar to a wound healing response with concomitant production of cytokines and mitogenic factor, including propigmentary factors [160]
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