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In the CNS, neurotransmission is profoundly disturbed in the absence of a normal gut microbiome (Clarke et al., 2013)

Frontiers in Endocrinology 14:1120533. [doi.org]

Causes, consequences and public health implications of low B-vitamin status in ageing

Factors like aging, poor diet, chronic stress, environmental toxins, and certain medical conditions can deplete the body's natural glutathione levels, making supplementation necessary for optimal health
[Abstract]2020 Sep 11;10(24):11159-11177
