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Genistein was able to induce apoptosis in human cervical cancer cells (HeLa cells) by enhancing the activities of each of caspase-9 and caspase-3, and/or both (Luo et al., 2014)

Mechanisms of ferroptosis Transport and storage of iron in the brain The neuronal iron metabolism related protein, TfR1 (transferrin receptor protein 1), is highly expressed on the surface of neurons (Giometto et al., 1990)

8 Future perspectives The gut microbiota can influence drug bioavailability and efficacy through metabolism, while most psychotropic medications possess anti-inflammatory properties and may directly alter microbial composition