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The regional selectivity finding is mechanistically credible, and the underlying receptor biology is well-established

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If you do not wish your name and contact information be made publicly available, you can provide this information on the cover sheet and not in the body of your comments and you must identify the information as confidential. Any information marked as confidential will not be disclosed except in accordance with 21 CFR 10.20 and other applicable disclosure law

Here, color refers to the pen casing and label, not the liquid inside