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Studies seeking drug candidates to induce the up-regulation of EAAT expression as a potential point of intervention in amyotrophic lateral sclerosis (ALS) demonstrated that some -lactam antibiotics could increase expression of EAAT2 through an action at the promoter level (Rothstein et al ., 2005)

Although no significant change in maternal blood pressure or uterine artery PI was observed, women receiving melatonin required less antihypertensive drugs compared to controls

The association between IGF-1 levels and the histologic severity of nonalcoholic fatty liver disease