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Recently a human hepatic enzyme was purified and identified as biphenyl hydrolase-like protein (BPHL)

Blocking NNMT activity has been shown in research settings to influence body composition, leading to reduced adipocyte size, alterations in fat mass, and measurable changes in plasma biomarkers such as glucose and cholesterol

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In addition, consisted with previous study 40 , we found that both inhalation treatment of TP-10@CaP in the high dosage and TP-10@CaP-CTP in the low dosage could ameliorate pulmonary congestion and injury, which induced by chronic heart failure (Supplementary Fig

But evidence is limited on long-term use, optimal dose, or maintenance