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10.1017/S1047951115000360

Astrocytes rely on ions to generate excitatory signals, compensating for their lack of electrical excitability 98

Developing cell-type-specific SIRT1 regulatorsfor example, hepatocyte-targeted molecules using GalNAc ligands or KC-specific nanoparticlesmay allow targeted activation, while selective inhibition in cells such as activated HSCs could also be explored

they add to carbonyl carbons instead (1,2-addition), as do organolithium reagents and LiAlH 4

Quorum sensing is one of the most important mechanisms that govern bacterial biofilm resistance against antibiotics, while the fimH gene plays a crucial role in bacterial virulence by contributing the fimbriae production