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After injecting paraquat-dichloride intraperitoneally, the researchers recorded an increase in ethane exhalation (oxidative stress marker) and observed lung tissue damage under the microscope

doi: 10.2174/1573399817666210101110253

Inflammation One pathway involved in TMAO-induced inflammation is the activation of protein kinase C (PKC) and NF-kB, increasing the expression of cell adhesion molecules such as VCAM1 and ICAM1, facilitating monocyte recruitment into the vessel wall, and increasing atherogenesis

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