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Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL

A.HosnedlovB.KizekR.AjsuvakovaO

C., Patrie, J

In particular, the particle size, surface morphology, and charge of the material play a crucial role in immunotoxicity and may cause reactive oxygen species production, DNA damage, lysosomal damage, mitochondrial dysfunction, and apoptosis or necrosis [175]

Parents of all subjects gave written informed consent and participants themselves gave assent when appropriate in accordance with the Declaration of Helsinki