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This could be due to an alteration in NMDA receptor gene expression, as major transcriptional factors such as the cAMP response element binding protein (CREB) are extremely sensitive to environmental stimuli [35]

Through interactions with intestinal cells, they help normalize permeability, stimulate mucus production, promote regeneration of the mucosal layer, and support the overall integrity and function of the intestinal barrier system (155)

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1 Introduction 1.1 Background The growing frequency and intensity of heat waves present a mounting global challenge
