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For example, in the spinal cord, the release of presynaptic opioids activates postsynaptic opioid receptors and promotes the opening of postsynaptic K + and/or Cl channels, evoking hyperpolarization inhibition potentials in dorsal horn neurons [13,38]

Neurotensin receptor Allosterism revealed in complex with a biased allosteric modulator

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Diffusion across the olfactory plate results in immediate delivery and has been shown to occur for small, water-soluble particles less than 1000 daltons (Da) in size