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Ultimately, this reprogramming of lipid metabolism leads to renal TECs apoptosis, tubular atrophy, and tubulointerstitial damage

Acknowledgements We thank Dave Primm (Department of Surgery, University of Texas Southwestern Medical Center) for his critical reading of the manuscript

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Left unchecked, oxidative stress causes cascading cellular and tissue damage 6

Figure 1 3 Formatting physiological changes in plants under heat stress High temperatures significantly impair critical physiological processes, particularly photosynthetic efficiency, which serves as a key indicator of photosystem functionality