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They narrowed it down to 36 total studies

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While this axis was initially thought to rely on neural and endocrine signaling, accumulating evidence now suggests that the immune system is a critical intermediary in gutbrain communication, forming what is increasingly recognized as the gutimmunebrain axis

In a recent randomized controlled trial on 34 individuals with mild cognitive impairment who were administered two periods of CGA (554 mg of CGA or placebo, twice/day) for 3 months with a monthly interval, data showed improvements in cognitive functions, especially attention and executive function [269]

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