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Our double-layered protein nanoparticles incorporating the full-length spike protein and the S2 stem induced robust and long-term immune responses and exhibited a safety profile in our primary studies, providing an option for current SARS-CoV-2 vaccine development. The pandemic is far from over, and new variants continue to emerge and pose a massive threat to human health

Caution is also advised in cases of hepatic impairment

Proprit de dtoxification de lorganisme Il joue un rle majeur dans la dfense de lorganisme en participant llimination de nombreux dchets et composs toxiques

To accommodate clinical manufacturing requirements, CVA21 purification was scaled-up and demonstrated at 100 L and 250 L process scales across seven batches (Table 2)