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The TCA cycle is an aerobic cycle, and therefore a lack of oxygen would preclude synthesis of succinyl-CoA and hence of heme
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Researchers suggest that glutathione may regulate vitamin D synthesis and metabolism and that GSH deficiency may contribute to vitamin D deficiency and, ultimately, increased critical and fatal cases of COVID-19
Fish Physiol Biochem 46:15611575
doi: 10.1016/s1590-8658(01)80045-1
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