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Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al

cGMP: Cyclic guanosine monophosphate

The discovery that early glycolytic intermediates could be used to fuel CFE also resulted in new systems combining multiple energy substrates and metabolic pathways in the extract

While the magnitude and direction of these effects likely depend on local cytokine tone and receptor stoichiometry, the presence of a DC-intrinsic TrkB pathway provides a mechanistic substrate for neurotrophin-driven remodeling of adaptive responses in OS

In contrast, we observed a significant reduction in protein expression of the TJ proteins, Occludin (37% of control, Figure 9C) and ZO-1 (50% of control, Figure 9B), along with a milder reduction in Claudin-5 expression (81% of control, Figure 9A)