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Accordingly, autophagy-mediated apoptosis stimulating agents, such as 9-tetrahydrocannabinol 40 and oncolytic adenovirus CRAd-Surivin-pk7 41 , combined with TMZ, were reported to strongly reduce the growth of glioma xenografts, suggesting that the combined administration of TMZ and autophagy inhibitors could be therapeutically exploited for the management of GBM

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Endo D, Fujimoto K, Hirose R, Yamanaka H, Homme M, Ishibashi KI, Miura N, Ohno N, and Aratani Y 2017