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From these plots, it is quite evident that G2C concentration of GSH favors this kind of interaction at maximum

To avoid further propagation of lipid peroxidation (LPO) and to attenuate oxidative stress, clearance of highly reactive lipid species is exerted by cancer cells through the activation of cellular antioxidant and free radical scavenging systems including ALDH enzymes (52) due to an increased NRF2-mediated expression of antioxidant enzymes as GPX3, SOD-2, and HO-1 (53)

World Journal of Experimental Medicine

Almikhlafi, Taibah University, Saudi Arabia Amer Ali, Cairo University, Egypt Updates Copyright 2025 ALSuhaymi, Alsugoor, Shokry, Fayed, Mohamed, Afifi, Esatbeyoglu, Korany and Elbaset
