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doi:10.1007/s10815-016-0751-z

27 This is a double-blind placebo-controlled study testing the safety and efficacy of ALC compared to placebo in the treatment of pain in HIV-positive patients with distal symmetric polyneuropathy related to antiretroviral drugs
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A study on Grave's disease pointed out that the increased levels of I-FABP and zonulin can damage intestinal epithelial cells through direct contact, toxin release and innate immune activation, which is probably due to the imbalance of microbiota

Seven relevant studies were included in the meta-analysis, which demonstrated that the combination of gabapentin and opioids effectively reduced pain intensity compared to opioids alone [69]
