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A three-year randomized, double-blind, placebo-controlled trial in 818 older adults (aged 50-70 years) with elevated homocysteine levels but normal serum vitamin B 12 levels found that folic acid supplementation (800 g/day) lowered homocysteine levels and improved measures of memory performance (115)

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Its research relevance is commonly associated with copper peptide, skin matrix, collagen, and extracellular matrix pathway research

The non-invasive nature of inhalation allows for ease of self-administration without the need for specialized equipment or health-care personnel 99,113

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