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Stimulation of GHRH by endorphins and enkephalins cannot be the only mechanism increasing GH release, however, as the met-enkephalin analogue DAMME is able to increase GH release over and above the levels released during maximal stimulation by a GHRH analogue (408)

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The enlargement of the distance between the cemento-enamel junction and the alveolar crest (crista alveolaris) is a clear sign of bone loss around the tooth

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An earlier landmark study by Staresinic et al
