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10.3390/cancers11111755 Summary Keywords oxidative stress, epigenetic marks, reactive oxygen species, animal models, drug discovery Citation Afzal S, Abdul Manap AS, Attiq A, Albokhadaim I, Kandeel M and Alhojaily SM (2023) From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration

6.2 Age Although C-19 is less common in children than adults, L-C19 and multisystem inflammatory syndrome (MIS-C) are long-term consequences observed in asymptomatic patients (153, 154)

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However, the dearth of long-term safety data and the elusive nature of the metabolic pathways of nanoparticles in the brain represent significant obstacles (Zhao et al., 2018)

9), indicating GPX4 deficiency potentiates oxidative stress and its feedback loop with GSDMD