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Description
3-AB is an early discovered PARP inhibitor, and its specificity is lower than newer PARP inhibitors developed for clinical use 176

Molecules (Basel, Switzerland) 25 (17), 3804
Detoxifying the body by binding to harmful substances and helping eliminate them

Pyruvate is a critical cataplerotic and anaplerotic substrate of the mitochondrial TCA cycle with important roles in gluconeogenesis, lipid synthesis, and NADH generation for the electron transport chain (ETC) (29)

Importantly, dietary changes or supplemental vitamins can eliminate many of the problems associated with the MTHFR variants