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The reason for the contradictory results in the in vitro experiments was probably the difference in the severity of the oxidation stress

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However, some people with B12 levels over 350 still have a deficiency

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and smell

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The early diagnosis of RA is often challenging due to the widespread symptoms reported by patients, including pain, swelling, stiffness, and functional impairment, many of which are also associated with other inflammatory diseases (Gibofsky 2014)

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The signs that matter clinically are carpal-tunnel-like wrist symptoms, persistent joint pain, or elevated blood glucose, these usually indicate IGF-1 is too high and dosing needs to be reduced

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