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It only affects new melanogenesis and not pre-existing pigmentation
However, pregnant women should always be referred to their physician if such measures are ineffective or if NVP symptoms are more severe
doi: 10.1186/1471-2431-11-111
Ferulic acid is a compound found in a variety of herbs and is of neuropharmacological interest as it readily penetrates the BBB [211]

Another study was undertaken to test the anti-inflammatory activity of shionone in a rat model