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For ultrastructural investigations, sections were poststained for 5 min with lead citrate and for 15 min with uranyl acetate at RT before they were observed with a Philips CM10 transmission electron microscope

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Collectively, this damage results in decreased melanocyte pigment-forming capacity and may even induce apoptosis through activation of inflammatory pathways such as the MAPK and p53 pathways.13 Saxena et al