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ExTraMATCH II study, a meta-analysis that evaluated data from 3990 patients and 13 randomized trials (including HF-ACTION trial) showed a reduced rate of hospitalization and improved quality of life (QOL) in HFrEF patients

Human gut microbiome: hopes, threats and promises

[DOI] [PubMed] [Google Scholar] 99.Weiss L., Zeira M., Reich S., Slavin S., Raz I., Mechoulam R., Gallily R

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1 Introduction The liver, among other body organs, holds a superior role in terms of physiological functions in synthesis, metabolism, detoxification, and immunity ( Acetaminophen is well tolerated at reasonable therapeutic doses with few adverse effects ( O -glucuronic acid), 55% of the dose, and O-sulfate, 30% of the dose, and is excreted in the urine ( In recent years, as a new research hotspot, Chinese herbal medicine has been widely applied ( Galla chinensis (GC) is a gall formed by a hornaphid or egg aphid in the host trees of Rhus chinensis , Populus cyanoplecta , or Red populus ( The gut microbiota plays an important role in maintaining the health of the host, and its balance can be affected by various external factors, including drugs, the environment, and a high-fat diet ( The TCMs are significant attention for their role in modulating the gut-liver axis, which plays an important role in the pathogenesis of various hepatic diseases ( 2 Materials and methods 2.1 Drug extraction Galla chinensis seeds were collected and processed to remove impurities as per standard protocols