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We observed no evidence of dominance effects ( P = 0.80), indicating that the allelic dosage of the T allele contributes to efficacy in an additive manner
[DOI] [PMC free article] [PubMed] [Google Scholar] Bymaster FP, Katner JS, Nelson DL, Hemrick-Luecke SK, Threlkeld PG, Heiligenstein JH, Morin SM, Gehlert DR, Perry KW (2002) Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder

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The frequency of the T allele in the study group was 19.6%, and the genotype frequencies of the CC, CT, and TT individuals were 69.6% (n = 39), 21.4% (n = 12), and 8.9% (n =5), respectively

D) Pyruvate kinase (Pyk) plays a key role in the production of pyruvate and ATP in glycolysis pathway and, moreover, as an essential factor in controlling the carbon flux distribution
