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CAFs are stromal cells within the tumor microenvironment that exhibit diverse biological characteristics, often demonstrating tumor-promoting activity

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For enrichment of the KEGG pathway, the intersection targets were mainly enriched in endocrine resistance, the estrogen signaling pathway, EGFR tyrosine kinase inhibitor resistance, and the HIF-1 signaling pathway, which may be the key pathways of luteolin in the anti-depressant effects

Alongside this growing interest, some reports have raised concerns about a potential link between NAD+ and cancer

Concerning CA characteristics, there was a predominance of out-of-hospital CA 62/71 (87%)