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The strong effects on spherogenicity in ZH-161 and ZH-305 may involve minor cytotoxic and antiproliferative effects of TGF-2 or EMD1214063 as demonstrated by changes in viability, cell cycle progression and increase of the cyclin-dependent kinase inhibitor p21 under these conditions (Supplementary Fig

Barrow-McGee R, Kishi N, Joffre C, Mnard L, Hervieu A, Bakhouche BA, et al

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Prenatal choline exposure alters hippocampal responsiveness to cholinergic stimulation in adulthood

In terms of the correlations between the severity of depression, as measured by CDI scores, and the studied metabolites at baseline, only the correlation of CDI with 5-HIAA was found to be significant (r=0.334, p=0.011, n=57)