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Cancer The complex role of ferroptosis in tumor treatment and tumorigenesis is not only affected by oncogenes and tumor suppressors, but also by the tumor microenvironment
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Pyruvate kinase M2 regulates the hypoxia-inducible factor 1-alpha (Hif-1) activity and IL-1 expression, being a key molecule to induce the Warburg effect in LPS-activated macrophages [117]
(5) GPx6 is expressed in the olfactory epithelium of humans and pigs [17]
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