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glutathione for cancer treatments Glutathione-responsive biodegradable polyurethane nanoparticles lung treatment Glutathione metabolism in cancer progression
Description
monocytogenes virulence in combination with phenotypic features (Stratakos et al., 2020

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Carbonyl cyanide m-chlorophenyl hydrazine renders the inner mitochondrial membrane permeable to H+, leading to membrane potential destabilisation on both sides of the inner mitochondrial membrane, and then, via the Pink1-Parkin pathway, which is specific for membrane potential destabilisation, the mitochondria undergo further membrane potential (MMP) hyperpolarisation, which generates ROS

ShenTYueYHeTHuangCQuBLvWet al

Under oxidative stress these three systems work in concert to detoxify ROS and lipid peroxides, maintain protein structure and function via thiol repair, prevent activation of redox-sensitive inflammatory pathways, and preserve mitochondrial membrane integrity and prevent apoptosis
