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( B ) Loss of RpoS was associated with production of antibodies against OspA
No human studies have confirmed this effect
K., Lee Y
Newborns (especially preterm) lack the ability to metabolize benzyl alcohol, leading to metabolic acidosis, respiratory distress, hypotension and (in reported cases) the often-fatal gasping syndrome. For this reason, only preservative-free sterile water (no benzyl alcohol) is used in pediatric or neonatal care
Notably, small molecule inhibitors have been identified that induce a conformational shift that precludes PrfA binding to DNA (Good et al., 2016
