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A U-shaped curve was found with force, with mortality values being lowest in the middle sextile and significantly higher in the lowest sextile (6.36 mmHg/ml, Figure, right panel)
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2020 doi: 10.1016/S2215-0366(20)30203-0
Date de mise jour : 4 nov
Given that p-cresyl sulfate, very similar to indoxyl sulfate, is notoriously difficult to eliminate by dialysis (Gryp et al., 2005), it is most likely that intervening the biosynthesis pathway is the best way to attenuate such toxic effect
