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Description
Functionalized pyridinone- and pyridinethione-scaffolds, nicotinic-, isonicotinic-, aminobenzoic- and hydrazinobenzoic acids were prepared and examined as bioisosters, but no significant improvement of affinity was encountered by this maneuver
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These studies underscore the importance of selecting appropriate chiral columns and mobile phase conditions for accurate separation and quantification of SFN enantiomers

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