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Gastrointestinal side effects are common upon initiation of metformin therapy but can also begin anew in patients who have taken metformin for many years

However, it can be continued during post-cycle to support recovery and metabolism

doi: 10.2174/157016111795495549 141 YanaiHAdachiHHakoshimaMKatsuyamaH
(Czechia) using validated chromatographic, spectrometric and mass spectrometry techniques