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According to plasma analysis of metabolomics using GCMS/MS, orotic acid additives impact twelve metabolites in plasma, including antioxidative uridine, 3-hydroxyanthranilic acid, tyrosine, glutamic acid, aspartic acid, and pyrimidines, according to GCMS/MS analysis of plasma metabolomics (182)

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285 Yet, they will be degraded by lactobacilli and bifidobacteria in the colon, promoting the growth of these bacteria while supplying SCFAs to colonic cells

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Cholesteryl ester synthesis in macrophages: stimulation by b-very low density lipoproteins from cholesterol fed animals of several species