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These compounds reduce the augmented pro-inflammatory iNOS and suppress cyclooxygenase (COX)-2 in LPS-stimulated monocyte/macrophage-like (RAW264.7) cells [79]
Skin dermal fibroblasts and epidermal keratinocytes express IGF-1R, and IGF-1 stimulation of these cells leads to proliferation and mitogenicity
Meanwhile, we also revealed the role of IHPC in resistance to chronic hypoxic injury, which provided a new perspective for the intervention of many hypoxia-related diseases
Ances, B
Targeting epidermal growth factor receptor and its downstream signaling pathways by natural products: a mechanistic insight
