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Intracellularly, rotenone primarily inhibits mitochondrial complex I, disrupting oxidative phosphorylation and impairing proteasomal function [90]

doi:10.1016/j.procbio.2005.02.027 Wen S, Zhang T, Tan T (2006) Maximizing production of glutathione by amino acid modulation and high-cell-density fed-batch culture of Saccharomyces cerevisiae

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