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Acerini CL, Patton CM, Savage MO, Kernell A, Westphal O, Dunger DB

The accumulation of GlcCer and GlcSph may disrupt autophagy, impair mitochondria, and promote -synuclein aggregation, although a solid recognized evidence linking decreased GCase activity with substrate accumulation and -synuclein build-up is still lacking (Rocha et al., 2015)

Common ones are mild and might include pain or redness at the injection site, mild diarrhea, or itching

Oxidative stress occurs when the body is overwhelmed by an excess of harmful molecules called free radicals, which it struggles to neutralise

DBZ increases the expression of transcription factors Ngn3 and Neurod1