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10.1101/gad.1783809 Genes Dev

LPS, a component of Gram-negative bacteria, binds to Toll-like receptor 4 (TLR4), activating NF-B and the NLRP3 inflammasome, leading to the release of IL-1 and TNF- (Page et al., 2022)

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Despite some reports on the similarities between senescence and eryptosis at the morphological level [67], intracellular Ca 2+ elevation [74], Ca 2+ -driven activation of Gardos channels [70], PS exposure [76], or ROS contribution [71], senescence of erythrocytes cannot be considered an RCD of these cells and should be clearly distinguished from eryptosis

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