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Conversely, excessive supplementation with exogenous antioxidants can weaken these positive ROS-mediated signals

Fresh solutions were prepared every 2 weeks, given at a dose of 0.1 ml (25 mg)/kg b.wt

Sulfide-rich fluids support unique ecosystems, where chemosynthetic bacteria and archaea utilize sulfur compounds as energy sources [21]

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Since this pathway use NADPH as electron donor, this compromises the availability of this coenzyme to regenerate reduced glutathione, exacerbating the oxidative stress [189]
