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For severe aortis stenosis or symptomatic individuals, surgery or transcatheter valve implantation is the only viable therapy option

Grades I/II and III/IV are also known as low-grade (LGG) and high-grade gliomas (HGG)

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The questionnaire used to assess pain is based on analogical measurement of pain intensity on a scale with 11 points, going from 0 to 10 (PI-NRS), where 0= no pain and 10= worst possible pain